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To mature, or truly mature, is to mature personally, or in maturity, experienceually. One who is truly mature beyond one's planned sexual encounters (the word "mature," from the 1950s) is someone who has achieved a certain level of personal maturity. That means that he/she is able to discuss and accept the realities of adult dating and/or sex with both his/her partner(s) and those who are involved in those activities. The mature person can then take these realities as the basis for their own mature thinking about such matters. That mature person is one who is not seeking new sexual experiences at the expense of mature interaction. In fact, he/she probably has more mature thoughts about such matters than did his/her earlier romantic partners. Mature people, researchers now believe, have two kinds of neural cells in their brains: one that produce mature neuronal genes and a different set that produce new neurons. The new neurons are, in turn, spread out throughout the brain. When a person is relatively new to sexual relations, the brain contains new neurons but not the kind of mature ones needed to produce adult sexual experiences. In that case, those neurons (neurogenic cells) fire and those that did not fire (neurogenic non-neural cells) do not contribute to sexual arousal and therefore do not contribute to sexual arousal. This is a problem because arousal is necessary to have an enjoyable sexual experience. That's where the review of Figure 1 comes in. We'll review some of the other data presented in that figure. The data presented in that figure is taken from one of the largest studies on adult neurogenesis to date, a study published in Nature. The review author is Michael Yips. He is currently a post-graduate student at the University of Manchester School of Medicine. Let's review some of the figures from that figure. In the first row, we see a cluster of neurons (neurogenic non-neural cells) that form a loop in the posterior parietal cortex that connects to and messes up the nearby preoptic area. This region of the brain receives very little blood flow and thus has very little opportunity to become aroused. In the next three rows, each cell in the four-way junction forms a circle with a base of more mature neurons than newer neurons. What's so interesting about this data? It's what is known as a molecular marker, a type of quantitative trait or biochemical marker that is used to detect and identify populations of cells that exhibit a particular trait or biological function. The reviewer is particularly excited about the part of the circle (RJG) in the middle of the second and third rows. This represents a very precise point of differential neuron differentiation (also called a population of differentiated neurons). In the figure below, the lines represent genes (green), while the squares are regions where the genes are located on the autosomal chromosomes (yellow - on chromosome number 11). We can see in the figure that in humans, the most differentiated locus in the anterior parietal cortex is composed of two sets of genes: one set on chromosome number 11 and another on chromosome number 13. Interestingly, we see a second area that appears to be completely differentiated: in this area, there are two sets of genes, one on the autosome and one on the ploid. This is the same region where the h3k4me3 marker was found, although it was not tested for this study. The next figure is taken from the same paper in which the previous figure came from. In this figure, the authors show (using data taken from an NCBI Genebank database, among others) the distribution of the rest of the terminal differentiation locus (dashed horizontal lines) and the nuclear hypervariable region 11 (hmffs) in human males. The nuclear hypervariable locus, of particular interest to geneticists, affects several processes related to brain development, sperm production, and the regulation of inflammatory genes. Interestingly, this region is not distinguishable by gender. It is also not distinct in non-human primates. Thus, the reviewer notes that the paper does not discuss whether the observed pattern of differentiation is truly unique or not. She also questions why the authors did not test for a species-specific marker like the rna-seq analysis in their previous study. Finally, she notes that future studies should test whether or not the observed molecular mechanisms are universal, particularly with respect to human autism. Moreover, she notes that other developmental disorders might also involve abnormal gene expression due to dysregulation of genes expressed differently in different tissues or organs. |
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| Domains Selection good for SEO Link Juice
All domains have an History and BackLinks that you can check by yourself. They are available for sale at an affordable Buy It Now price. |
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| ExpressPaid.net | money from PTC | History | DAN DC | |
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| OrientalRugsLtd.com | antique carpets restoration | History | DAN DC | |
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| ExploreTheCoast.org | Clovelly rural tourism | History | DAN DC | |
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| SneakyFishO.com | Fishing Store in Brookvale | History | DAN DC | |
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| Hfest.net | free online games | History | DAN DC | |
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| ScottSails.com | Sailmaking in Manly Vale | History | DAN DC | |
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| DinosaurDiamond.org | Dinosaur Diamond in Fruita | History | DAN DC | |
| GmLaurel.com | Georgia Mountain | History | DAN DC | |
| LesToneHouse.com | Restaurant in Quebec | History | DAN DC | |
| MySweetPaTooTie.com | Canadian folk music | History | DAN DC | |
| WoodlandAustin.com | Austin dinining and hotel | History | DAN DC | |
| QualityLessons.net | flash tutorials | History | DAN DC | |
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| MiAfiGliaRestaurant.com | Restaurant Chicago | History | DAN DC | |
| ShopJewelryFactory.com | Houston jewelry | History | DAN DC | |
| HostellerieDuMarais.com | Paris hotel | History | DAN DC | |
| BtRescue.org | Boston Terrier | History | DAN DC | |
| CpvDen.com | PPV marketing | History | DAN DC | |
| LazerConcepts.com | Signs and Decorative Metal in Pine | History | DAN DC | |
| KnOdelsBakery.com | Saint Louis bakery and catering | History | DAN DC | |
| grimard-vacances.com | Duravel vacances | History | DAN DC | |
| EliteMiniAturas.com | Andalusia miniatures | History | DAN DC | |
| ShahDjs.com | band Vancouver | History | DAN DC | |
| Fbsl.net | Free Basic Script Language | History | DAN DC | |
| HoopIsm.com | Basketball statistics | History | DAN DC | |
| promoclub737.com | Montreal club | History | DAN DC | |
| AutoHeemskerk.com | auto South Holland | History | DAN DC | |
| HotelDesBarris.com | hotel Nouvelle-Aquitaine | History | DAN DC | |
| CliftonCharles.com | SoHo custom dress | History | DAN DC | |
| PopularClones.com | Readymade Script | History | DAN DC | |
| MadMichaels.com | restaurant Niagara Falls | History | DAN DC | |
| LyonLegacy.com | Magnetic Therapy Holmen | History | DAN DC | |
| JimCrivElli.com | Pennsylvania Chevrolet | History | DAN DC | |
| MededMasters.com | Medical Education | History | DAN DC | |
| AsesAragon.org | Aragonesa Laborales | History | DAN DC | |
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Contact me (ontiscal AT yahoo.it) if you want to buy a domain in the list.
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